Macie has been to over 68 countries, 16 of those performing stand-up comedy with the USO. She was a finalist on NBC's Last Comic Standing in 2006. Macie has appeared on E! Entertainment, Fuel TV, HSN, Sirius and XM Radio. Programs she has been on include Bob & Tom, Access Hollywood, and The Todd and Tyler Radio Empire, and she was labeled an "emerging talent to watch" by The Hollywood Reporter at the Just for Laughs Comedy Festival in 2005. Macie was a regular guest on the Howard Stern Show, where in 2008 she was voted the "Funniest and Hottest" comedian in America. She has appeared on Showtime in the documentary, I Am Comic which premiered at the 2010 Slamdance Film Festival and in the stand-up special Vegas Is My Oyster premiering August 5. Macie was a featured performer in Snoop Dogg Presents The Bad Girls of Comedy which aired on Showtime in 2012. Macie performed on Episode 5 of the Netflix Series, Tiffany Haddish Presents: They Ready in 2019. Currently, she spends most of her time traveling the United States as a headlining stand-up comedian.